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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCND1
All Species:
20
Human Site:
S225
Identified Species:
48.89
UniProt:
P24385
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24385
NP_444284.1
295
33729
S225
R
S
P
N
N
F
L
S
Y
Y
R
L
T
R
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101029
295
33581
S225
G
S
P
N
N
F
L
S
Y
Y
R
L
T
R
F
Dog
Lupus familis
XP_854586
289
32654
T224
D
E
D
V
S
S
L
T
G
D
A
L
V
D
L
Cat
Felis silvestris
Mouse
Mus musculus
P25322
295
33410
S225
G
S
P
N
N
F
L
S
C
Y
R
T
T
H
F
Rat
Rattus norvegicus
P39948
295
33464
S225
G
S
P
N
N
F
L
S
C
Y
R
T
T
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506630
241
27203
L193
I
K
C
D
P
D
C
L
R
A
C
Q
E
Q
I
Chicken
Gallus gallus
P55169
292
33245
S225
G
N
T
N
T
F
L
S
Y
Q
C
L
T
H
F
Frog
Xenopus laevis
P50755
291
32935
S223
G
N
A
D
S
V
F
S
T
Q
R
L
T
L
F
Zebra Danio
Brachydanio rerio
Q90459
291
33049
S225
K
S
T
D
S
C
L
S
S
Q
N
L
T
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396634
330
36829
L226
T
G
K
S
G
Y
G
L
A
G
L
L
D
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
62.7
N.A.
93.9
93.9
N.A.
71.1
86
77.6
76.2
N.A.
N.A.
46.6
N.A.
N.A.
Protein Similarity:
100
N.A.
99.3
77.2
N.A.
95.9
96.2
N.A.
77.2
92.5
88.4
89.1
N.A.
N.A.
63.6
N.A.
N.A.
P-Site Identity:
100
N.A.
93.3
13.3
N.A.
73.3
73.3
N.A.
0
53.3
33.3
40
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
93.3
26.6
N.A.
73.3
73.3
N.A.
13.3
60
53.3
60
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
10
10
10
0
0
0
0
% A
% Cys:
0
0
10
0
0
10
10
0
20
0
20
0
0
0
0
% C
% Asp:
10
0
10
30
0
10
0
0
0
10
0
0
10
10
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
10
10
0
% E
% Phe:
0
0
0
0
0
50
10
0
0
0
0
0
0
0
70
% F
% Gly:
50
10
0
0
10
0
10
0
10
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
10
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
70
20
0
0
10
70
0
10
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
0
50
40
0
0
0
0
0
10
0
0
10
0
% N
% Pro:
0
0
40
0
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
30
0
10
0
10
0
% Q
% Arg:
10
0
0
0
0
0
0
0
10
0
50
0
0
20
0
% R
% Ser:
0
50
0
10
30
10
0
70
10
0
0
0
0
0
0
% S
% Thr:
10
0
20
0
10
0
0
10
10
0
0
20
70
0
0
% T
% Val:
0
0
0
10
0
10
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
30
40
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _